Robert L. Grubb III, M.D.

Urology Surgery
Assistant Professor, Surgery
Division of Urologic Surgery

Board Certification:
Board Certified in Urology

Areas of Specialty and Clinical Interest:
Dr. Grubb specializes in urologic cancer surgery. His areas of specialty include prostate cancer and kidney cancer, both localized and metastatic. Additionally, he is experienced at managing patients with hereditary kidney cancer syndromes such as Von Hippel-Lindau and Birt-Hogg-Dubé. Dr. Grubb performs both open and laparoscopic surgeries. He is interested in prostate cancer imaging, using MRI. Other areas of interest include bladder cancer, testicular cancer, penile cancer and adrenal disorders such as pheochromocytoma and aldosteronoma, elevated PSA and blood in the urine.

Medical School:
Emory University School of Medicine, Atlanta, GA, 1996

Postdoctoral Education:
General Surgery Residency: Washington University School of Medicine, 1998

Urology Residency: Washington University School of Medicine, 2002

Clinical Fellowship: National Cancer Institute, Bethesda, MD, Urologic Oncology Branch, 2005

Patients Seen At:
Center for Advanced Medicine
Urologic Surgery Center
4921 Parkview Place, Suite C, Floor 11
St. Louis, MO 63110
(314) 454-8775
Fax: (314) 454-5244

Barnes-Jewish West County Hospital
Professional Office Building #1
1040 North Mason Road, Suite 122
St. Louis, MO 63141
(314) 996-8060

Patient Appointments:
(314) 362-8200

Hospital Affiliations:
Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Research Interest:
Prostate cancer screening and epidemiology

Cell signaling and molecular targeted therapeutics for prostate cancer

Evaluation and treatment of hereditary kidney cancer syndromes

Prostate cancer imaging with MRI

Awards/Honors:
Morris Abrams Award for Excellence in Urologic Patient Care, 2000, 2001

Aronberg Award for Academic Achievement in Urology, 2002

International Volunteers in Urology Traveling Scholarship, Haiti, 2002

Gerald P. Murphy Scholar, AUA, 2002

Selected or Recent Publications:
Skolarus TA, Wolin KY, Grubb RL 3rd. The effect of body mass index on PSA levels and the development, screening and treatment of prostate cancer. Nature Clinical Practice. Urology. 2007;4(11):605-614.

Grubb RL 3rd, Franks ME, Toro J, Middelton L, Choyke L, Fowler S, Torres-Cabala C, Glenn GM, Choyke P, Merino MJ, Zbar B, Pinto PA, Srinivasan R, Coleman JA, Linehan WM. Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer. Journal of Urology. 2007;177(6):2074-2079; discussion 2079-2080.

Pinsky PF, Kramer BS, Crawford ED, Grubb RL, Urban DA, Andriole GL, Chia D, Levin DL, Gohagan JK. Prostate volume and prostate-specific antigen levels in men enrolled in a large screening trial. Urology. 2006;68(2):352-356.

Grubb RL 3rd, Vardi IY, Bhayani SB, Kibel AS. Minimally invasive approaches to localized prostate carcinoma. Hematology/Oncology Clinics of North America. 2006;20(4):879-895.

Grubb RL 3rd, Andriole GL. Can preoperative PSA doubling time and PSA velocity predict outcomes following radical prostatectomy? Nature Clinical Practice, Urology. 2006;3(6):306-307.

Grubb RL, Roehl KA, Antenor JA, Catalona WJ. Results of compliance with prostate cancer screening guidelines. Journal of Urology. 2005;174:668.

Ménard C, Susil RC, Choyke P, Coleman J, Grubb R, Gharib A, Krieger A, Guion P, Thomasson D, Ullman K, Gupta S, Espina V, Liotta L, Petricoin E, Fitchtinger G, Whitcomb LL, Atalar E, Coleman NC, Camphausen K. An interventional MRI technique for the molecular characterization of intra-prostatic dynamic contrast enhancement. Molecular Imaging. 2005;4(1):63.

Wei MH, Toure O, Glenn G, Pithukpakorn M, Neckers L, Stolle C, Choyke P, Grubb R, Middleton L, Turner ML, Walther M, Merino M, Zbar B, Linehan WM, Toro JR. Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer. J Med Genetics. 2005

Grubb RL 3rd, Choyke PL, Pinto PA, Linehan WM, Walther MM. Management of von-Hippel-Lindau-associated kidney cancer. Nat Clin Pract Urol. 2005;2:248.

Grubb RL, Pavlovich CP, Hurley K Glenn GM, Toro J, Schmidt LS, Torres-Cabala C, Merino MJ, Zbar B, Choyke PL, Walther MM, Linehan WM: Evaluation and management of renal tumors in the Birt-Hogg-Dubé syndrome. Journal of Urology. 2005;173:1482.

Andriole GA, Levin DL, Crawford ED, Gelmann EP, Pinsky PF, Chia D, Kramer BS, Reding D, Church TR, Grubb RL, Izmirlian G, Ragard LR, Clapp JD, Prorok PC, Gohagan JK for the PLCO Project Team: Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: Findings from the Initial Screening Round of a Randomized Trial. Journal of the National Cancer Institute. 2005;97:433-438.

Kundu SD, Grubb RL, Roehl KA, Antenor JA, Han M, Catalona WJ. Delays in cancer detection using 2 and 4-year screening intervals for prostate cancer screening with initial prostate specific antigen less than 2 ng/mL. Journal of Urology. 2005;173:1116-1120.

Linehan WM, Grubb RL, Coleman JA, Zbar B, Walther MM. The genetic basis of kidney cancer: implications for gene specific clinical management. BJU International. 2005;95 Suppl 2:2-7.

Pub Med page for Robert L. Grubb III, M.D.

Selected or Recent Chapters:
Grubb RL III, Linehan WM, Walther MM. Management of Inherited Forms of Renal Cancer. In: Vogelzang N (ed.). Comprehensive Textbook of Urologic Oncology. Philadelphia: Lippincott, Williams and Wilkins; 2005:750-755.

Grubb RL, Figenshau RS. Urologic Surgery. In: Doherty G (ed.). Washington Manual of Surgery. Philadelphia: Lippincott, Williams and Wilkins; 2002:687-705.

Grubb RL, Andriole GL. Evaluation of Prostate Cancer. In: Kursh ED, Ulchaker JC (eds.). Office Urology. Totowa, NJ: Humana Press, Inc.; 2001:255-264.

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